Since there are numerous brands for Sildenafil Citrate, buyers sometimes are confused which to prefer, as sometimes they are forced to choose between Kamagra vs Delgra. But which brand is really the best for erectile dysfunction? The choice between Kamagra vs Delgra may be hard, as both drugs contain the same active pharmaceutical ingredient (API), which is Sildenafil Citrate. Both treatments target the condition erectile dysfunction (ED), which is one disease common to the male population.
Erectile dysfunction is a condition where a man has difficulty in gaining control over his erectile response. Patients who are suffering from erectile dysfunction find it extremely hard for them to attain an erection and when they do, the response is always insufficient; they also fail to maintain an erection even if they are sexually aroused. We can put the blame for erectile dysfunction on the morphology of the vascularity of the male penis; when a male gets old or contracts chronic diseases, the blood vessels which surround the penis gets narrower, so little flow come in. The blood flow is an important aspect of erection, so cutting the blood supply to the penile tissue significantly affects the erectile response of an individual.
Aside from the morphological factors affecting the pathophysiology of erectile dysfunction, we can also attribute the disease to trauma or injury to the spinal column, drugs (some drugs are able to cause erectile dysfunction as a side effect), or sometimes the disease is in the mind. Because the sexual response is an integral part of living, the need to treat erectile response in males came to be.
Kamagra vs Delgra: PDE5 Inhibitors
Between Kamagra vs Delgra, there is no difference in their composition. Both drugs contain the same Sildenafil Citrate, the active pharmaceutical ingredient also present in the brand-name treatment Viagra. Sometimes, these two (Kamagra and Delgra) are termed “generic Viagra” for easier reference. Brand-name and generic drugs for erectile dysfunction are identical in terms of their API which makes them effective. Sildenafil Citrate belongs to the family of PDE5Is or Phosphodiesterase Type-5 Inhibitors (along with Tadalafil and Vardenafil). These drugs are the main choices for oral treatments for erectile dysfunction, mainly because they are a lot cheaper than the invasive medical procedures intended for erectile dysfunction.
Sildenafil is the mainstream treatment for erectile dysfunction and it is popularized by Pfizer in 1998. Erectile dysfunction has existed before, but the whole world seemed reserved regarding the topic. Erectile dysfunction is a disease, but since the condition is sensitive, the patients affected by the disease are often embarrassed to talk about their condition, therefore limiting the scope of the study on the dysfunction. But since the world opened up to the treatment of erectile dysfunction, there had been numerous developments in the area of treatment for the disease. However, until now, there is no cure for erectile dysfunction. Patients can use PDE5 inhibitors as much as they want, but the effect of the PDE5I treatments only lasts as long as the drug is in their system.
How do PDE5 inhibitors function? These drugs help the patients regain their erectile function by inhibiting the enzyme PDE5 which blocks cGMP or cyclic guanosine monophosphate. Cyclic GMP has the lead role in the erectile response; it is the one which allows the relaxation of the smooth muscles of the penis in order for the blood to flow freely in the spongy penile tissue, thus mediating erection. In patients with ED, PDE5 destroys cGMP prematurely so the erection could not take place or could not be maintained. Sildenafil and the other PDE5 inhibitors suppress the action of the PDE5 enzyme to allow the patients regain their erectile response for a few hours.
Kamagra vs Delgra: How are they used?
Since Kamagra and Delgra are both Sildenafil products, their use is basically the same—the patients should take them for at least an hour before their intended sexual activity. Kamagra vs Delgra products are also advised to be taken without food for a faster effect. Although there are varying dosage strengths for Kamagra and Delgra (they come in 25 mg, 50 mg, 100 mg, 150 mg, and 200 mg forms), patients are only allowed to take one dose of the drug within 24 hours. This should strictly be observed, as patients who double their doses of Sildenafil are at risk for greater and more severe incidences of side effects. Sildenafil products like Kamagra and Delgra also decrease the blood pressure too, so taking more than the required dose of the drug in a day puts them at risk of having an extremely low blood pressure. Also, there is no daily recommendation for the intake of Sildenafil, so the patients only have to take Sildenafil-containing products only when needed.
Since Sildenafil products across the board (either brand-name or generic) have the same active ingredient, their side effects are also the same. Between Kamagra vs Delgra, the side effects are the same too. Patients can expect both products to cause them headaches, nausea, flushing, dyspepsia, nasopharyngitis, stuff/runny nose, and gastrointestinal problems, as these side effects are common to the patients during the clinical trial testing of Sildenafil Citrate in ED patients.
There are also special considerations for the use of Kamagra and Delgra; Sildenafil products, generic or brand-name, should not be used by patients in conjunction with their nitrate medication (for angina, other cardiovascular medications, hypertension meds, and others) like nitroglycerin and isosorbide mono/dinitrate. The use of Sildenafil products with these drugs can cause extremely low blood pressure in patients.
Patients with liver disease or liver metabolism problems are also not allowed to take the either Kamagra or Delgra since the Sildenafil drugs like them are metabolized in the liver. If the liver does not excrete the by-products of these drugs properly, the patients may experience Sildenafil toxicity.
Kamagra vs Delgra: Comparison
Let us first discuss the manufacturers of the drugs; Kamagra is manufactured by Ajanta Pharma, while Delgra is made by the company Delta Enterprises. Both companies are from India, although Ajanta Pharma is a more established company than Delta Enterprises. Ajanta Pharma has been in the pharmaceutical business since 1973, while Delta Enterprises is a younger company and was inducted only in 2009.
Both are manufacturers and exporters of finished pharmaceutical formulations, though, but Ajanta Pharma has a larger reach than Delta Enterprises, which only supplies its product to several countries (Russia, Ukraine, Singapore, Mauritius, and Hong Kong). But, for a young company, Delta Enterprises is not an ordinary company for it to be able to export its products to various countries. As for the certifications, Delta Enterprises prides itself in its ISO 9001: 2008, ISO 14001: 2004, ISO 17025-2005(NABL), WHO-GDSK North Zone, and WHO-GMP. Ajanta Pharma, on the other hand, is also WHO-GMP certified and also has a US FDA approval for one of its plants and a number of its products. Looking at these credentials, we can say that both companies are credible and reliable when it comes to manufacturing.
Delta Enterprises, the manufacturer of Delgra has its focus on the production of men’s health products (ED, premature ejaculation, hair loss), women’s health products primarily for female sexual dysfunction, weight loss products, and smoking cessation products. For Sildenafil (Delgra), it has varying doses of the traditional pills (25, 50, 100, 150, and 200 mg), chewable tablets, soft gel capsules, combination drugs and oral jellies, which are similar to the product offerings of Ajanta Pharma. The company Ajanta has an extensive product line (has 1400 products to its name) with Sildenafil drugs similar to that of Delta, but with additions like the candy polo types and effervescent tablets. There is not much of a difference in these two companies’ drug offerings.
As for the price, we can also say that there is little price difference between Kamagra vs Delgra:
The price difference of Kamagra and Delgra is just a matter of $0.20 for the minimum purchase, but when the buyers purchase in bulk, they can save more on Delgra. Considering the function of these two drugs are the same and their manufacturers are both credible, buyers can consider buying either of the treatments.
There are also reviews available for both medications online from satisfied customers, although the reviews for Delgra were harder to find. This may be due to its lesser popularity than Kamagra on the online market. Overall, these two generic drugs are interesting and are recommendable to try. Both of their manufacturers have certifications for good manufacturing processes which are compliant with the international laws for product manufacturing. Kamagra vs Delgra products are also similar, as both companies have almost the same products for ED treatment (Sildenafil Citrate). Not all companies have a product line as extensive as these two for erectile dysfunction, and for that, it is good to give them credit. Under the advice and direct supervision of the doctors, both Kamagra and Delgra are products worth trying.